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The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens.

Identifieur interne : 000594 ( Main/Exploration ); précédent : 000593; suivant : 000595

The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens.

Auteurs : Félix Gutiérrez [Espagne] ; Mar Masiá ; Carlos Mirete ; Bernardo Soldán ; J Carlos Rodríguez ; Sergio Padilla ; Ildefonso Hernández ; Gloria Royo ; Alberto Martin-Hidalgo

Source :

RBID : pubmed:16375972

Descripteurs français

English descriptors

Abstract

OBJECTIVES

To determine the population-based incidence of community-acquired pneumonia (CAP) in adults and to assess the relative importance of age and gender on the incidence of infections caused by different microbial pathogens.

METHODS

A two-year prospective study in a well-defined geographic area of the Spanish Mediterranean coast.

RESULTS

The overall incidence rate of CAP was 12 cases (95% CI 11.25-13.45) per 10,000 person-years. Incidence rates increased by age (p<0.0001) and they were higher in males (16 versus 9 cases per 10,000 person-years; p<0.0001). The rate was especially high among males aged > or = 75 years (87 cases per 10,000 person-years). The incidence of pneumococcal pneumonia increased significantly with ageing and it was particularly high among people aged > or = 75 years (10 cases per 10,000 person-years). Very elderly people had also a 15-fold higher incidence of CAP associated with influenza virus and a 5-fold higher incidence of infections by Chlamydophila spp., than young adults. The incidence of infections with Legionella pneumophila also increased with age and it was 10 times higher in males. In contrast, the incidence of pneumonia caused by Mycoplasma pneumoniae was unrelated to age and gender.

CONCLUSIONS

Age and gender have a strong influence on the overall incidence of CAP and on the incidence of pneumonia caused by the main microbial pathogens, including not only Streptococcus pneumoniae, but also influenza virus, Chlamydophila spp. and L. pneumophila. Ageing is associated with a higher risk of acquiring pneumonia by S. pneumoniae, influenza virus and Chlamydophila spp., whereas male gender increases greatly the incidence of L. pneumophila and Chlamydophila spp.


DOI: 10.1016/j.jinf.2005.11.006
PubMed: 16375972


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Aging (physiology)</term>
<term>Chlamydophila pneumoniae (isolation & purification)</term>
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<term>Humans (MeSH)</term>
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<term>Chlamydophila pneumoniae (isolement et purification)</term>
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<term>Infections communautaires (épidémiologie)</term>
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<b>OBJECTIVES</b>
</p>
<p>To determine the population-based incidence of community-acquired pneumonia (CAP) in adults and to assess the relative importance of age and gender on the incidence of infections caused by different microbial pathogens.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
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<p>A two-year prospective study in a well-defined geographic area of the Spanish Mediterranean coast.</p>
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<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>The overall incidence rate of CAP was 12 cases (95% CI 11.25-13.45) per 10,000 person-years. Incidence rates increased by age (p<0.0001) and they were higher in males (16 versus 9 cases per 10,000 person-years; p<0.0001). The rate was especially high among males aged > or = 75 years (87 cases per 10,000 person-years). The incidence of pneumococcal pneumonia increased significantly with ageing and it was particularly high among people aged > or = 75 years (10 cases per 10,000 person-years). Very elderly people had also a 15-fold higher incidence of CAP associated with influenza virus and a 5-fold higher incidence of infections by Chlamydophila spp., than young adults. The incidence of infections with Legionella pneumophila also increased with age and it was 10 times higher in males. In contrast, the incidence of pneumonia caused by Mycoplasma pneumoniae was unrelated to age and gender.</p>
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<b>CONCLUSIONS</b>
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<p>Age and gender have a strong influence on the overall incidence of CAP and on the incidence of pneumonia caused by the main microbial pathogens, including not only Streptococcus pneumoniae, but also influenza virus, Chlamydophila spp. and L. pneumophila. Ageing is associated with a higher risk of acquiring pneumonia by S. pneumoniae, influenza virus and Chlamydophila spp., whereas male gender increases greatly the incidence of L. pneumophila and Chlamydophila spp.</p>
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<AbstractText Label="RESULTS" NlmCategory="RESULTS">The overall incidence rate of CAP was 12 cases (95% CI 11.25-13.45) per 10,000 person-years. Incidence rates increased by age (p<0.0001) and they were higher in males (16 versus 9 cases per 10,000 person-years; p<0.0001). The rate was especially high among males aged > or = 75 years (87 cases per 10,000 person-years). The incidence of pneumococcal pneumonia increased significantly with ageing and it was particularly high among people aged > or = 75 years (10 cases per 10,000 person-years). Very elderly people had also a 15-fold higher incidence of CAP associated with influenza virus and a 5-fold higher incidence of infections by Chlamydophila spp., than young adults. The incidence of infections with Legionella pneumophila also increased with age and it was 10 times higher in males. In contrast, the incidence of pneumonia caused by Mycoplasma pneumoniae was unrelated to age and gender.</AbstractText>
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<name sortKey="Soldan, Bernardo" sort="Soldan, Bernardo" uniqKey="Soldan B" first="Bernardo" last="Soldán">Bernardo Soldán</name>
</noCountry>
<country name="Espagne">
<noRegion>
<name sortKey="Gutierrez, Felix" sort="Gutierrez, Felix" uniqKey="Gutierrez F" first="Félix" last="Gutiérrez">Félix Gutiérrez</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeEspagneV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000594 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000594 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    GrippeEspagneV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:16375972
   |texte=   The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:16375972" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GrippeEspagneV1 

Wicri

This area was generated with Dilib version V0.6.37.
Data generation: Fri Sep 25 11:01:38 2020. Site generation: Sat Feb 13 17:38:04 2021